In a large mixing bowl, combine the cream cheese, chili, cumin, onion powder, garlic powder, salt, pepper, cilantro, green onions, chicken and shredded cheese. Mix thoroughly until well combined.
On a work surface, spread 2 of the tortillas. Spoon some of the mixture over the bottom of each tortilla.
Top with another tortilla.
Heat a large nonstick skillet with cooking spray over medium heat. Carefully place 1 quesadilla in pan and cook 2 minutes.
Using a spatula, gently flip the quesadilla and cook an additional 2 minutes until lightly browned and the cheese is melted. Repeat with second quesadilla.
Serve warm with your favorite salsa.